Location History:
- Kensington, NH (US) (2002)
- San Diego, CA (US) (2013 - 2021)
Company Filing History:
2 out of 7 
1 out of 1 
3 out of 832,718 Years Active: 2002-2021
Title: Innovations of Patrick M McDonough
Introduction
Patrick M McDonough is a notable inventor based in San Diego, CA. He has made significant contributions to the field of cellular analysis, holding a total of 6 patents. His work focuses on the quantitative analysis of action potentials, calcium transients, and ionic flux in excitable cells.
Latest Patents
One of his latest patents involves the analysis of action potentials, transients, and ion flux in excitable cells. This innovative method utilizes video recordings from two or more optical channels that are produced, processed, and analyzed simultaneously. The goal is to provide a quantitative analysis of action potentials, calcium transients, and ionic flux in excitable cells that are loaded with voltage or ion-sensitive dyes. These dyes have distinct excitation and emission wavelengths, allowing for the separation and recording of specific wavelengths of fluorescent light emitted from each dye. The recordings are mutually registered, and cytometric analysis is performed to provide a detailed analysis on a cell-by-cell and well-by-well basis in microtiter plates. After the cells are fixed and labeled for other biomarkers, they are scanned again. The resulting fixed cell images are registered with the live cell recordings, enabling the detection of missing cells that may have been washed off. Cytometry data from both live and fixed cell scans is collated on a cell-by-cell basis.
Career Highlights
Throughout his career, Patrick has worked with various companies, including Vala Sciences, Inc. His expertise in cellular analysis has positioned him as a key figure in the field, contributing to advancements in understanding cellular behavior and dynamics.
Collaborations
Patrick has collaborated with notable individuals such as Jeffrey H Price and Fabio Cerignoli, further enhancing the impact of his work in the scientific community.
Conclusion
Patrick M McDonough's innovative contributions to cellular analysis through his patents and collaborations have significantly advanced the understanding of excitable cells. His work continues to influence the field and inspire future research.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.