The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 19, 2016

Filed:

Feb. 22, 2013
Applicants:

David J. Charlot, La Jolla, CA (US);

Randall S. Ingermanson, Battleground, WA (US);

Patrick M. Mcdonough, San Diego, CA (US);

Jeffrey H. Price, San Diego, CA (US);

Inventors:

David J. Charlot, La Jolla, CA (US);

Randall S. Ingermanson, Battleground, WA (US);

Patrick M. McDonough, San Diego, CA (US);

Jeffrey H. Price, San Diego, CA (US);

Assignee:

Other;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/02 (2006.01); G06T 7/00 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/02 (2013.01); G06T 7/0016 (2013.01); G06T 2207/10016 (2013.01); G06T 2207/10056 (2013.01); G06T 2207/10064 (2013.01); G06T 2207/20152 (2013.01); G06T 2207/20216 (2013.01); G06T 2207/30024 (2013.01);
Abstract

A method, system, and instrument for automatically measuring transient activity in cells uses image time sequences to identify transients in cells. Preferably, the transient activity is stimulated or provoked in synchronism with acquisition of the image time sequences. A cell mask is applied to each image of an image time sequence in order to localize the transient activity with respect to each cell. Localization enables cell-by-cell analysis of properties of the transient activity.


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