Company Filing History:
Years Active: 2022-2025
Title: The Innovative Contributions of Patricia Ann Cruite
Introduction
Patricia Ann Cruite, based in Medford, MA, is a distinguished inventor known for her significant contributions to the field of biomedicine. With a focus on antibody development, she holds two patents that reflect her dedication to advancing therapeutic methods for various disorders.
Latest Patents
One of Patricia's notable patents is for "Anti-CD45 antibodies and conjugates thereof." This invention discloses a series of anti-CD45 antibodies and antibody-drug conjugates (ADCs) that specifically target human CD45. These antibodies play a crucial role in therapeutic methods aimed at depleting CD45+ cells, which can be particularly beneficial for treating cancers and autoimmune disorders. Furthermore, this invention can prepare patients for hematopoietic stem cell transplants by depleting existing CD45+ cells to enhance engraftment success.
The second patent, "CD8-specific antibody constructs and compositions thereof," details antibodies that bind specifically to human CD8, alongside fusion proteins that incorporate Henipavirus glycoprotein G. This innovative approach allows for targeted cell transduction in those expressing CD8, showcasing her contributions to viral vector technology and targeted therapy.
Career Highlights
Patricia has worked with leading companies in the biotechnology sector, including Vor Biopharma Inc. and Sana Biotechnology, Inc. Her work has significantly impacted the development of novel therapeutic strategies, demonstrating her expertise in antibody engineering and cell-targeting technologies.
Collaborations
Throughout her career, Patricia has collaborated with talented professionals, including her coworkers Anthony Boitano and Michael Cooke. These collaborations have played a pivotal role in the advancement of her innovative work, combining diverse expertise to drive forward the research and development of groundbreaking biomedical therapies.
Conclusion
Patricia Ann Cruite stands out as a trailblazer in the field of biomedicine through her innovative inventions and collaborative efforts. Her patents serve as a testament to her commitment to improving therapeutic approaches for complex health conditions, making a lasting impact in the realm of biomedical research and development.