The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 27, 2022
Filed:
Apr. 07, 2022
Applicant:
Sana Biotechnology, Inc., Seattle, WA (US);
Inventors:
Patricia Ann Cruite, Medford, MA (US);
Shirisha Amatya, Cambridge, MA (US);
Hugh Harding, Framingham, MA (US);
Lauren Pepper MacKenzie, Belmont, MA (US);
Assignee:
Sana Biotechnology, Inc., Seattle, WA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/86 (2006.01); C07K 16/28 (2006.01); C07K 14/705 (2006.01); C07K 14/725 (2006.01); A61P 35/00 (2006.01); A61P 35/04 (2006.01); C07K 14/005 (2006.01); A61K 39/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); A61P 35/00 (2018.01); A61P 35/04 (2018.01); C07K 14/005 (2013.01); C07K 14/7051 (2013.01); C07K 14/70517 (2013.01); C07K 14/70521 (2013.01); C07K 14/70578 (2013.01); C07K 16/2803 (2013.01); C07K 16/2815 (2013.01); A61K 38/00 (2013.01); A61K 2039/505 (2013.01); A61K 2039/545 (2013.01); C07K 2317/569 (2013.01); C07K 2317/622 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C07K 2319/02 (2013.01); C07K 2319/33 (2013.01); C12N 2740/15043 (2013.01); C12N 2760/18222 (2013.01); C12N 2760/18233 (2013.01); C12N 2760/18271 (2013.01);
Abstract
Disclosed herein are antibodies or antigen binding fragments thereof that specifically bind human CD8. Also disclosed are fusion proteins comprising a Henipavirus glycoprotein G and CD8 antibodies for targeting and transducing cells expressing CD8. Viral vectors and other compositions containing the fusion proteins, as well as methods of using the fusion proteins, are also disclosed.