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Title: Pat Wals: Innovator in Amyloid Beta Research
Introduction
Pat Wals is a notable inventor based in Los Angeles, CA (US). He has made significant contributions to the field of biomedical research, particularly in the study of amyloid beta proteins. With a total of 2 patents, his work focuses on understanding and manipulating the molecular structures associated with neurodegenerative diseases.
Latest Patents
Wals' latest patents revolve around the invention of amyloid beta-derived dementing ligands (ADDLs). These ligands consist of amyloid beta peptide assembled into soluble globular non-fibrillar oligomeric structures. They are capable of activating specific cellular processes. The patents encompass methods for assaying the formation, presence, receptor protein binding, and cellular activities of ADDLs. Additionally, they describe assay methods and inhibitor molecules for cellular signaling molecules activated by ADDLs. Furthermore, the inventions include molecules that block proteins promoting the formation of ADDLs.
Career Highlights
Throughout his career, Pat Wals has worked with prestigious institutions, including Northwestern University. His research has contributed to a deeper understanding of the mechanisms underlying neurodegenerative diseases, paving the way for potential therapeutic interventions.
Collaborations
Wals has collaborated with notable colleagues such as Grant A. Krafft and William L. Klein. Their combined expertise has further advanced the research in amyloid beta proteins and their implications in health.
Conclusion
Pat Wals is a distinguished inventor whose work on amyloid beta proteins has the potential to impact the field of neurodegenerative disease research significantly. His innovative patents and collaborations highlight his commitment to advancing scientific knowledge and improving health outcomes.