Company Filing History:
Years Active: 2011
Title: The Innovative Mind of Pascale Charest in Biosensor Technology
Introduction
Pascale Charest, an accomplished inventor based in San Diego, CA, is making waves in the field of biosensor technology. With a passion for advancing scientific understanding, she has developed a unique biosensor that provides valuable insights into receptor activity and signaling molecules.
Latest Patents
Charest holds a noteworthy patent titled "Double brilliance beta-arrestin: a biosensor for monitoring the activity of receptors and signaling molecules, and method of using same." This patent unveils an innovative intramolecular bioluminescence resonance energy transfer (BRET) biosensor. It is designed to monitor receptor activity and signaling cascades by sandwiching β-arrestin between luciferase and the yellow fluorescent protein (YFP). This groundbreaking technology allows for the study of native receptors in large-scale screening analysis, improving our understanding of receptor dynamics in living cells.
Career Highlights
Charest's career is marked by a commitment to innovation and scientific research. Her work has led to the development of the double-brilliance biosensor, which not only improves our comprehension of agonist-induced conformational rearrangements of β-arrestin but also has potential applications in monitoring other signaling molecules that interact with β-arrestin.
Collaborations
In her quest for knowledge, Pascale collaborates with esteemed coworker Michel Bouvier. Together, they contribute to the advancement of receptor studies, which holds significant implications for the fields of pharmacology and biotechnology.
Conclusion
Pascale Charest's contributions to biosensor technology through her innovative patent are paving the way for new discoveries in receptor biology. As she continues her work with Valorisation-recherche, Limited Partnership, the scientific community looks forward to the advancements that will emerge from her research.