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Title: The Innovative Work of Inventor Pascal Andre Stein in the Field of Anti-CD19 Antibodies
Introduction: Pascal Andre Stein is a distinguished inventor based in Boston, MA, known for his significant contributions to the biomedical field. With a total of 7 patents to his name, Stein is at the forefront of developing innovative solutions in antibody technology that address critical medical challenges.
Latest Patents: Stein's most recent work focuses on the development of Anti-CD19 antibodies with reduced immunogenicity. He has disclosed the Anti-CD19 B4 antibodies featuring modified variable regions designed to alter framework regions or complementarity determining regions in heavy and light chain variable regions. These modifications aim to reduce T-cell responses, thereby enhancing the antibodies' therapeutic potential while minimizing adverse immune reactions.
Career Highlights: Stein has gained extensive experience working in reputable organizations such as Merck Patent GmbH and EMD Lexigen Research Center Corp. His tenure at these companies has been instrumental in honing his skills as an inventor and advancing his research in antibody therapies.
Collaborations: Throughout his career, Stein has collaborated with prominent figures in the field, including Kin-Ming Lo and Stephen D. Gillies. These partnerships have fostered a collaborative environment, enriching his research and innovation endeavors.
Conclusion: With a notable portfolio of patents and a commitment to advancing antibody technology, Pascal Andre Stein continues to make significant strides in the biomedical industry. His work not only showcases his inventiveness but also promises to impact patient care positively through innovative therapies.