Company Filing History:
Years Active: 1987-1994
Title: Innovations by Paolo Fabrizi
Introduction
Paolo Fabrizi is a notable inventor based in Monteriggioni, Italy. He has made significant contributions to the field of biochemistry, particularly in the development of innovative solutions for medical applications. With a total of three patents to his name, Fabrizi's work has the potential to impact various aspects of healthcare.
Latest Patents
Fabrizi's latest patents include a human sera dilution buffer solution containing the enzyme collagenase. This solution is designed to prevent false positive indication reactions when specific IgMs are sought in human sera by ELISA capture assays. The enzymatic conjugate consists of antibodies bound to alkaline phosphatase (ALP) with glutaraldehyde. Another significant patent involves a method and reagent composition for the determination of alanine. This method colorimetrically determines the enzyme alanine aminotransferase (ALT) as the hydrogen peroxide obtained in the pyruvate hydrolysis reaction catalyzed by the enzyme pyruvate oxidase. The reagent composition is buffered at a pH between 7.0 and 7.5 and includes L-alanine, ketoglutaric acid, and a source of inorganic phosphorus. This method is particularly useful for checking the suitability of blood intended for transfusions, allowing for the simultaneous testing of hepatitis B surface antigen (HBsAg) and ALT in the same serum specimen.
Career Highlights
Fabrizi works at Sclavo Spa, a company known for its advancements in medical diagnostics and biochemistry. His role at the company has allowed him to focus on developing innovative solutions that address critical healthcare challenges. His patents reflect his commitment to improving diagnostic methods and ensuring the safety of blood transfusions.
Collaborations
Fabrizi collaborates with esteemed colleagues such as Francesco Donnini and Alessandro Tabacco. Their combined expertise contributes to the innovative projects at Sclavo Spa, fostering an environment of creativity and scientific advancement.
Conclusion
Paolo Fabrizi's contributions to the field of biochemistry through his patents and collaborations highlight his dedication to innovation in healthcare. His work not only enhances diagnostic methods but also plays a crucial role in ensuring patient safety.