This inventor holds 1 USPTO granted patent. Top assignee: Pyrosequencing Ab. Active years: 2001.
Company Filing History:
Years Active: 2001
Title: Pål Nyren: Innovator in DNA Sequencing
Introduction
Pål Nyren is a notable inventor based in Skarpnäck, Sweden. He has made significant contributions to the field of biotechnology, particularly in DNA sequencing. His innovative methods have paved the way for advancements in genetic research and diagnostics.
Latest Patents
Pål Nyren holds a patent for a method of sequencing DNA. This invention provides a method of identifying a base at a target position in a single-stranded sample DNA sequence. The process involves an extension primer that hybridizes to the sample DNA immediately adjacent to the target position. The sample DNA and extension primer are subjected to a polymerization reaction in the presence of a deoxynucleotide or dideoxynucleotide. The incorporation of the deoxynucleotide or dideoxynucleotide occurs only if it is complementary to the base in the target position. The release of pyrophosphate is detected enzymatically, and pyrophosphate detection enzyme(s) are included in the polymerization step. This innovative approach enhances the accuracy and efficiency of DNA sequencing.
Career Highlights
Pål Nyren is associated with Pyrosequencing AB, a company that specializes in DNA sequencing technologies. His work has been instrumental in developing methods that are widely used in genetic analysis and research. His contributions have significantly impacted the field of molecular biology.
Collaborations
Pål Nyren has collaborated with notable scientists such as Mostafa Ronaghi and Mathias Uhlen. These collaborations have further advanced the research and development of DNA sequencing technologies.
Conclusion
Pål Nyren's innovative work in DNA sequencing has made a lasting impact on biotechnology. His patented methods continue to influence genetic research and diagnostics, showcasing the importance of innovation in science.