Location History:
- Charlottesville, VA (US) (2018 - 2021)
- Charlottsville, VA (US) (2021)
Company Filing History:
Years Active: 2018-2021
Title: Innovations by Panagiotis Mastorakos
Introduction
Panagiotis Mastorakos is a prominent inventor based in Charlottesville, VA, known for his significant contributions to the field of gene delivery systems. With a total of six patents to his name, he has made remarkable strides in developing innovative solutions for overcoming biological barriers in medical applications.
Latest Patents
Mastorakos's latest patents include "Highly stable biodegradable gene vector platforms for overcoming biological barriers." This invention addresses the challenges in non-viral gene delivery by providing a safe and effective delivery system. The gene vectors are designed to be biodegradable, non-toxic, and highly customizable for specific applications. They consist of a mixture of biodegradable copolymers and hydrophilic polymers, demonstrating broad vector distribution and high transgene delivery in vivo.
Another notable patent is "Selective dendrimer delivery to brain tumors." This composition involves poly(amidoamine) (PAMAM) hydroxyl-terminated dendrimers that are covalently linked to therapeutic agents for treating brain tumors. The dendrimers exhibit high uptake into the brain, allowing for selective delivery of various agents through the blood-brain barrier. This innovation provides a promising approach for simultaneous delivery of multiple therapeutic compounds.
Career Highlights
Panagiotis Mastorakos is affiliated with The Johns Hopkins University, where he continues to advance research in gene delivery systems. His work has garnered attention for its potential impact on therapeutic applications, particularly in the treatment of brain tumors and other medical conditions.
Collaborations
Mastorakos collaborates with esteemed colleagues, including Justin Scot Hanes and Jung Soo Suk, who contribute to the research and development of innovative medical solutions.
Conclusion
Panagiotis Mastorakos is a leading inventor whose work in biodegradable gene vectors and dendrimer delivery systems is paving the way for advancements in medical therapies. His contributions are vital in addressing significant challenges in the field of gene delivery, showcasing the importance of innovation in healthcare.