Location History:
- Reading, PA (US) (2013)
- Reading, MA (US) (2011 - 2018)
Company Filing History:
7 out of 1,309 
1 out of 2,597 
Years Active: 2011-2018
Title: The Innovative Contributions of Pamela Kelley
Introduction
Pamela Kelley is a distinguished inventor based in Reading, MA (US), known for her significant contributions to the field of biotechnology. With a total of 7 patents to her name, she has made remarkable strides in developing methods for treating various degenerative disorders.
Latest Patents
Kelley’s latest patents include groundbreaking methods for treating muscle wasting syndrome and sarcopenia using antagonist antibodies against growth and differentiation factor-8 (GDF-8). These disclosures provide novel molecules, particularly mouse and humanized antibodies, and antibody fragments that inhibit GDF-8 activity and signaling both in vitro and in vivo. The methods outlined in her patents aim to diagnose, treat, ameliorate, prevent, prognose, or monitor degenerative disorders of muscle, bone, and insulin metabolism, with a particular focus on amyotrophic lateral sclerosis (ALS). Additionally, her patents include pharmaceutical compositions for treating these disorders using the antibodies, polypeptides, polynucleotides, and vectors she has developed.
Career Highlights
Throughout her career, Pamela Kelley has worked with notable organizations such as Wyeth and the University of Pennsylvania. Her work has significantly impacted the understanding and treatment of muscle-related disorders, showcasing her dedication to advancing medical science.
Collaborations
Kelley has collaborated with esteemed colleagues, including Frank S. Walsh and Margaret Maria Zaleska, further enhancing her research and innovation in the field.
Conclusion
Pamela Kelley’s innovative work and numerous patents reflect her commitment to improving health outcomes through biotechnology. Her contributions continue to pave the way for advancements in the treatment of degenerative disorders.