P Scott White

Title: P Scott White: Innovator in Nucleic Acid Detection Technologies

Introduction

P Scott White is a notable inventor based in Los Alamos, NM (US). He has made significant contributions to the field of molecular biology, particularly in the detection of nucleic acid sequences. With a total of 2 patents, his work has advanced the methodologies used in genetic analysis.

Latest Patents

One of his latest patents is focused on "Nucleic acid sequence detection using multiplexed oligonucleotide PCR." This invention describes methods for rapidly detecting single or multiple sequence alleles in a sample nucleic acid. The patent provides oligonucleotide pairs that can specifically anneal to target alleles, allowing for the formation of an oligonucleotide complex when a particular sequence feature is present or absent. This complex enables high-level PCR amplification of a specific amplicon, which is crucial for detecting the allele. Various detection methods, including oligonucleotide capture onto DNA chips or microarrays, are also discussed in this patent.

Another significant patent by White is titled "DNA polymorphism identity determination using flow cytometry." This invention involves primers that are immobilized on microspheres, which anneal to the DNA strand under investigation. The primers are then extended or ligated to fluorescent reporter oligonucleotides, allowing for the measurement of fluorescence by flow cytometry. This process identifies nucleotide polymorphisms on the DNA strand, showcasing the innovative techniques developed by White.

Career Highlights

Throughout his career, P Scott White has worked with prestigious organizations such as the University of California and Los Alamos National Security, LLC. His experience in these institutions has allowed him to collaborate with leading experts in the field and contribute to groundbreaking research.

Collaborations

Some of his notable coworkers include John P Nolan and Hong Cai. Their collaborative efforts have further enhanced the impact of White's inventions in the scientific community.

Conclusion

P Scott White's contributions to nucleic acid detection technologies have paved the way for advancements in genetic analysis. His innovative patents reflect his expertise and commitment to improving methodologies in molecular biology.