Company Filing History:
Years Active: 2019-2020
Title: P Audrey Brozozog Lee: Innovator in Single-Domain Antibody Technology
Introduction
P Audrey Brozozog Lee is a notable inventor based in Washington, DC, with a focus on advancements in single-domain antibody technology. He holds a total of 3 patents that contribute significantly to the field of biochemistry and therapeutic development.
Latest Patents
His latest patents include innovative work on single-domain antibody fusion proteins with the acid tail of alpha-synuclein. This patent describes a method for producing a single-domain antibody (sdAb) by causing bacteria to express the sdAb in their cytoplasm, where it is expressed as a fusion protein. Notably, the protein is free of a periplasmic location tag, and these antibodies exhibit the unexpected ability to refold after thermal denaturation. Another significant patent involves nucleic acids for single-domain antibodies with thermal stability under cytoplasmic expression, further emphasizing the potential of sdAbs in therapeutic applications.
Career Highlights
P Audrey Brozozog Lee is currently associated with the United States Navy, where he contributes his expertise in antibody technology. His work is pivotal in advancing the understanding and application of single-domain antibodies in various medical fields.
Collaborations
He collaborates with esteemed colleagues such as Daniel Zabetakis and George P Anderson, enhancing the research and development efforts in his area of expertise.
Conclusion
P Audrey Brozozog Lee's contributions to the field of single-domain antibodies are noteworthy, and his innovative patents reflect his commitment to advancing biotechnological solutions. His work continues to pave the way for future developments in therapeutic applications.