Orly Mouallem

Title: Orly Mouallem: Innovator in Pharmaceutical Compounds

Introduction

Orly Mouallem is a prominent inventor based in Rechovot, Israel. She has made significant contributions to the field of pharmaceuticals, particularly in the development of compounds that modulate heparanase activity. Her innovative work has the potential to impact the treatment of various diseases associated with heparanase and heparin-binding proteins.

Latest Patents

Orly Mouallem holds a patent for "Rigidified compounds for modulating heparanase activity." This patent discloses novel rigidified compounds that feature a rhodanine-like residue and at least one aryl or heteroaryl residue linked to the rhodanine-like residue. The core structure of these compounds is characterized by having one or zero free-to-rotate bonds. Additionally, the patent outlines pharmaceutical compositions containing these rigidified compounds and their uses in treating heparanase-associated diseases and disorders.

Career Highlights

Orly is associated with Insight Biopharmaceuticals Ltd., where she continues to advance her research and development efforts. Her work focuses on creating innovative solutions for medical conditions that can be treated with rhodanine or its analogs.

Collaborations

Orly has collaborated with notable colleagues, including Joel M Van Gelder and Joseph Y Klein. These partnerships have further enhanced her research capabilities and contributed to her success in the field.

Conclusion

Orly Mouallem's contributions to pharmaceutical innovations demonstrate her commitment to advancing medical science. Her patent on rigidified compounds showcases her ability to develop solutions for complex health issues.