Wallingford, CT, United States of America

Omar D Lopez

USPTO Granted Patents = 37 

 

 

Average Co-Inventor Count = 7.3

ph-index = 11

Forward Citations = 422(Granted Patents)


Location History:

  • Wallingford, CT (US) (2005 - 2017)
  • Walkersville, MD (US) (2020 - 2022)

Company Filing History:


Years Active: 2005-2022

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37 patents (USPTO):

Title: Omar D Lopez: Innovating Stereoselective Synthesis and Manufacturing of 2'-Deoxynucleosides

Introduction:

Omar D Lopez, an accomplished inventor and researcher hailing from Wallingford, CT, has made significant contributions to the field of chemistry and pharmaceutical sciences. With an impressive portfolio of 37 patents, Lopez's groundbreaking work in stereoselective synthesis and manufacturing techniques has revolutionized the production of 2'-deoxynucleosides. In this article, we explore his latest patents, highlight his career accomplishments, collaborations, and conclude with the impact of his innovative contributions.

Latest Patents:

Lopez's recent patents showcase his expertise in the stereoselective synthesis and manufacturing of 2'-deoxynucleosides. One notable patent is the "Stereoselective synthesis and process for the manufacturing of 2'-deoxynucleosides." This invention presents novel methods for producing 2'-deoxynucleosides, specifically emphasizing the β-anomer configuration with a 3' α hydroxyl and 4' β hydroxymethyl group. The patented process enables the production of compounds like 4'-thio-2'-deoxycytidine (T-dCyd) and 5-aza-4'-thio-2'-deoxycytidine (5-aza-T-dCyd).

Another significant patent is the "2'-halogenated-4'-thio-2'-deoxy-5-azacytidine analogs and use thereof." This invention encompasses the development of halogenated analogs of 5-aza-2'-deoxycytidine, specifically focusing on halogenated analogs of 5-aza-4'-thio-2'-deoxycytidine (5-aza-T-dCyd). These compounds have shown promise in the field of neoplasia inhibition, making them potential candidates for the development of pharmaceutical compositions.

Career Highlights:

Throughout his career, Lopez has worked with prominent organizations such as Bristol-Myers Squibb Company and the United States of America, represented by the Secretary of the Department of Health and Human Services. His work with these prestigious institutions has contributed to their advancements in the field of chemistry and pharmaceuticals.

Collaborations:

Lopez's dedication to innovation and scientific progress is evident in his collaborations with esteemed colleagues. Notably, he has worked alongside Makonen Belema and Nicholas A Meanwell. These collaborations have fostered an environment of knowledge exchange and collective problem-solving, ultimately leading to groundbreaking advancements in the field.

Conclusion:

Omar D Lopez's journey as a scientist and inventor has paved the way for novel methodologies in the stereoselective synthesis and manufacturing of 2'-deoxynucleosides. His patents and extensive research highlight his commitment to advancing pharmaceutical sciences. Through his collaborations and affiliations with prestigious organizations like Bristol-Myers Squibb Company, and the United States of America, Lopez has contributed to the overall progress and understanding of chemistry and pharmaceuticals. We eagerly anticipate further groundbreaking innovations from this influential figure.

Disclaimer: The information provided in this article is based on publicly available data and research materials, aiming to present an overview of Omar D Lopez's work.

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