Company Filing History:
Years Active: 2006
Title: Innovations by Olaf Pongs in Potassium Channel Therapeutics
Introduction
Olaf Pongs is a notable inventor based in Hamburg, Germany. He has made significant contributions to the field of biochemistry, particularly in the development of therapeutics targeting voltage-gated potassium channels. His work has implications for various medical applications, especially in cardiac and neurological health.
Latest Patents
Olaf Pongs holds a patent for a novel tension-dependent potassium channel protein known as Kv6.2. This invention relates to the Kv6.2 gene, which is primarily expressed in the myocardium and the hippocampus. The patent describes the formation of novel functional heteromultimeric potassium channels that exhibit high affinity with propafenone when combined with the subunit Kv2.1. These potassium channels are utilized in test systems designed to identify substances that can modulate, open, or close the Kv2.1/Kv6.2 channels, which may serve as therapeutic agents.
Career Highlights
Olaf Pongs is associated with Evotec OAI AG, a company known for its innovative approaches in drug discovery and development. His work at Evotec has allowed him to collaborate with leading scientists and contribute to groundbreaking research in the field of pharmacology.
Collaborations
One of his notable collaborators is Rainer Netzer, with whom he has worked on various projects related to potassium channel research. Their combined expertise has led to advancements in understanding the therapeutic potential of these channels.
Conclusion
Olaf Pongs is a distinguished inventor whose work on voltage-gated potassium channels has the potential to revolutionize therapeutic approaches in medicine. His contributions continue to influence the field and pave the way for future innovations.