The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 10, 2006

Filed:

Aug. 06, 1999
Applicants:

Rainer Netzer, Hamburg, DE;

Olaf Pongs, Hamburg, DE;

Inventors:

Rainer Netzer, Hamburg, DE;

Olaf Pongs, Hamburg, DE;

Assignee:

Evotec Oai AG, Hamburg, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/06 (2006.01); C07K 1/00 (2006.01); C07H 21/04 (2006.01); C12N 15/00 (2006.01); C12N 1/20 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to a novel tension-dependent potassium channel protein Kv6.2 (SEQ ID NO:1). The Kv6.2 gene is expressed preferably in the myocardium or in the hippocampus. Novel functional heteromultimeric potassium channels having high affinity with propafenone are formed in conjunction with subunit Kv2.1. According to the invention, said novel potassium channels are used in test systems which are suitable of identifying substances modulating, opening or closing the Kv2,1/Kv6.2 channels and which can be used as therapeutic agents.


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