Oladapo Bakare

Title: Innovations of Oladapo Bakare in Cancer Treatment

Introduction

Oladapo Bakare is an accomplished inventor based in Beltsville, MD (US). He has made significant contributions to the field of cancer treatment through his innovative work on emetine derivatives. With a total of 3 patents, his research focuses on developing prodrugs that selectively activate in cancerous environments.

Latest Patents

Bakare's latest patents include groundbreaking compounds that are emetine derivatives. These compounds can be utilized as prodrugs, which selectively undergo activation to release emetine in specific cellular conditions. A notable aspect of his work involves incorporating a blocking group onto the emetine molecule by derivatizing the N2'-position with moieties that can be selectively removed by hydrolysis in the cancer/tumor microenvironment. These compounds are designed to be less cytotoxic than emetine and are substantially inactive in non-cancerous cells. His research indicates that these compounds can be effective in treating both metastatic and non-metastatic cancers, including breast cancer, prostate cancer, lung cancer, and leukemia.

Career Highlights

Throughout his career, Bakare has worked with prestigious institutions, including Howard University. His innovative research has positioned him as a key figure in the development of targeted cancer therapies.

Collaborations

Oladapo Bakare has collaborated with notable professionals in his field, including Samuel Ray Denmeade and Emmanuel S Akinboye. These collaborations have further enhanced the impact of his research and innovations.

Conclusion

Oladapo Bakare's contributions to cancer treatment through his innovative emetine derivatives highlight the potential for targeted therapies in oncology. His work continues to pave the way for advancements in the treatment of various cancers.