Nubuo Nagai

Title: Nubuo Nagai: Innovator in Yeast Expression Technology

Introduction

Nubuo Nagai is a prominent inventor based in Leuven, Belgium. He has made significant contributions to the field of biotechnology, particularly in the development of yeast expression systems for recombinant proteins. His work has implications for medical treatments, especially in addressing thrombotic diseases.

Latest Patents

Nagai holds a patent for a yeast expression vector and a method of making a recombinant protein by expression in a yeast cell. This patent details vectors for the expression in yeast of mammalian plasminogen derivatives, such as microplasminogen and miniplasminogen. The methods disclosed in the patent facilitate the expression of these proteins in a methylotrophic yeast expression system, along with their activation and stabilization. The proteins developed through this invention are utilized in the treatment of focal cerebral ischemic infarction and other thrombotic diseases.

Career Highlights

Nubuo Nagai is associated with Thromb-x NV, a company focused on innovative solutions for thrombotic conditions. His expertise in yeast expression technology has positioned him as a key figure in the biotechnology sector. His work not only advances scientific knowledge but also contributes to potential therapeutic applications.

Collaborations

Nagai has collaborated with notable professionals in his field, including Désiré José Collen and Yves Laroche. These collaborations have further enriched his research and development efforts, leading to advancements in the application of yeast expression systems.

Conclusion

Nubuo Nagai's contributions to yeast expression technology and recombinant protein development highlight his role as an influential inventor in biotechnology. His work continues to pave the way for innovative treatments in medicine.