Location History:
- Machida, JA (1976 - 1977)
- Machida, JP (1979 - 1987)
Company Filing History:
10 out of 730 
2 out of 45 
Years Active: 1976-1987
Title: Nobuhiro Nakamizo: Innovator in Pharmaceutical Chemistry
Introduction
Nobuhiro Nakamizo is a prominent inventor based in Machida, Japan. He has made significant contributions to the field of pharmaceutical chemistry, holding a total of 12 patents. His work primarily focuses on developing compounds with therapeutic applications, particularly in the treatment of hypertension.
Latest Patents
Nakamizo's latest patents include innovative compounds such as the 1-benzyl-3,5-dimethyl-4-piperdyl ester of a Hantzsch dihydropyridine. This compound is noted for its ability to maintain a less rapid decrease in blood pressure when used as an antihypertensive. Another notable patent involves 1,4-dihydropyridine derivatives, specifically an optical isomer that exhibits hypotensive activity. The hydrochloride of this compound has melting points ranging from 196°C to 202°C, making it suitable for use in pharmaceutical compositions.
Career Highlights
Throughout his career, Nakamizo has worked with notable companies such as Kyowa Hakko Kogyo Co., Ltd. and Kyowa Hakko Kogyo Kabushiki Kaisha. His experience in these organizations has allowed him to refine his expertise in pharmaceutical development and innovation.
Collaborations
Nakamizo has collaborated with esteemed colleagues, including Masayuki Teranishi and Kenji Muto. These partnerships have contributed to the advancement of his research and the successful development of his patented compounds.
Conclusion
Nobuhiro Nakamizo's contributions to pharmaceutical chemistry through his innovative patents highlight his role as a key inventor in the field. His work continues to impact the development of effective antihypertensive medications.