This inventor holds 2 USPTO granted patents. Top assignees: Technion Research & Development Foundation Ltd, Tel Aviv University. Active years: 2017-2018.
Company Filing History:
2 out of 1,001 
2 out of 840 
Years Active: 2017-2018
Title: Innovations of Nir Osherov in Amphotericin B Derivatives
Introduction
Nir Osherov is a notable inventor based in Tel Aviv, Israel. He has made significant contributions to the field of pharmaceuticals, particularly in the development of Amphotericin B derivatives. With a total of 2 patents to his name, his work focuses on enhancing the efficacy and safety of antifungal treatments.
Latest Patents
Osherov's latest patents revolve around the creation of derivatives of Amphotericin B that exhibit increased solubility and reduced toxicity compared to the original compound. These derivatives maintain antifungal activity against various clinical fungal isolates. The inventions include a polymer group with an amine group linked to mycosamine via a stable amide linker. The general formula of these derivatives allows for various substitutions, including hydrogen, alkyl, or phenyl groups, and incorporates water-soluble polymers along with pharmaceutically acceptable salts and prodrugs.
Career Highlights
Throughout his career, Nir Osherov has been associated with prominent institutions such as the Technion Research & Development Foundation Ltd and Tel Aviv University. His work in these organizations has facilitated advancements in pharmaceutical research and development.
Collaborations
Osherov has collaborated with notable colleagues, including Itai Benhar and Vladimir Dergachev. Their combined expertise has contributed to the innovative research in the field of antifungal treatments.
Conclusion
Nir Osherov's contributions to the development of Amphotericin B derivatives highlight his role as a significant inventor in the pharmaceutical industry. His work not only enhances the effectiveness of antifungal treatments but also aims to improve patient safety.