Cambridge, MA, United States of America

Ning Shen

USPTO Granted Patents = 4 

 

Average Co-Inventor Count = 8.0

ph-index = 2

Forward Citations = 8(Granted Patents)


Company Filing History:


Years Active: 2019-2022

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4 patents (USPTO):

Title: Inventor Ning Shen: Pioneering Advances in Genetic Treatment

Introduction

Ning Shen, an accomplished inventor located in Cambridge, MA, is known for his significant contributions to genetic research and treatment methodologies. With a portfolio that includes four patents, Shen is making strides in the realm of biotechnology and its applications for treating genetic disorders.

Latest Patents

Shen's latest patents focus on the use of p38 inhibitors to effectively reduce the expression of DUX4, a gene associated with several diseases, including Facioscapulohumeral muscular dystrophy (FSHD). His first patent outlines compositions and methods for inhibiting p38 kinase, which in turn can decrease the gene and protein expression of DUX4 along with related downstream genes. This discovery has pivotal implications for developing treatments for patients affected by conditions linked to increased DUX4 expression.

In his subsequent patent, Shen elaborates on the methods and compositions utilizing p38 kinase inhibitors and agents that regulate the expression of DUX4 and its downstream genes. This patent presents potential therapeutic methods for addressing diseases related to abnormal DUX4 expression, thereby reaffirming the significance of his research in the field of muscular dystrophy.

Career Highlights

Ning Shen's career is marked by his affiliation with Fulcrum Therapeutics, Inc., where he contributes his expertise to advance therapeutic solutions. His role emphasizes the intersection of invention and practical application, generating innovative strategies to combat genetic disorders through scientific discovery and patenting.

Collaborations

Throughout his career, Shen has worked alongside talented professionals like Angela Marie Cacace and Luis Gustavo Alejandro Rojas Soto. These collaborations foster an environment for shared ideas and enhanced research outputs, underscoring the importance of teamwork in driving innovation.

Conclusion

As a dedicated inventor, Ning Shen's work is shaping the future of genetic treatments, particularly in combating Facioscapulohumeral muscular dystrophy. His patents not only showcase his innovative spirit but also signify a commitment to improving patient outcomes through advanced therapeutic methodologies. With a strong career foundation and collaborative partnerships, Shen is poised to continue his impactful journey in the field of biotechnology.

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