This inventor holds 1 USPTO granted patent. Top assignee: Amersham International Plc. Active years: 1994.
Company Filing History:
Years Active: 1994
Title: Nicos D Christofides: Innovator in Biological Assays
Introduction
Nicos D Christofides is a notable inventor based in Cardiff, GB. He has made significant contributions to the field of biological assays, particularly in the measurement of ligands in biological fluids. His innovative approach has paved the way for advancements in medical diagnostics.
Latest Patents
Nicos D Christofides holds a patent for a "Method for measuring the free fraction of ligands in biological fluids." This one-step assay allows for the determination of the free portion of a ligand in a biological sample. The method involves incubating a mixture of the sample with a labelled antibody for the ligand and a ligand analogue that competes for binding to the antibody. The assay is characterized by selecting a ligand analogue with a lower affinity for the antibody than the ligand itself. The binding affinity of the insolubilised ligand analogue is ideally between 0.01% to 10% of that of the ligand. Exemplified ligand/ligand analogue pairs include T4/T3 (Thyroxine/Tri-iodothyronine), Testosterone/etiocholanol, and T3/T2.
Career Highlights
Nicos D Christofides is associated with Amersham International Plc, where he has contributed to various projects in the field of biological research. His work has been instrumental in enhancing the accuracy and efficiency of biological assays.
Collaborations
Throughout his career, Nicos has collaborated with esteemed colleagues such as Christopher P Sheehan and John E Midgley. These collaborations have further enriched his research and innovation in the field.
Conclusion
Nicos D Christofides is a distinguished inventor whose work in biological assays has had a profound impact on medical diagnostics. His innovative methods continue to influence the field, showcasing the importance of research and development in healthcare.