Company Filing History:
Years Active: 2009-2012
Title: **Nicole M. Piche: Innovating Protein Production**
Introduction
Nicole M. Piche is a distinguished inventor located in Waltham, MA, specializing in innovative systems and methods for protein production. With a total of two patents to her name, she has made significant contributions to the field of biotechnology, particularly through her work in genetic engineering.
Latest Patents
Nicole's latest inventions focus on enhancing protein production using genetically-engineered animal or plant cells. One notable patent outlines systems and methods that employ modified protein folding or processing capacities. This invention features genetically-engineered cells that contain recombinant expression cassettes, which encode both a protein of interest and a polypeptide that is functional within the unfolded protein response (UPR) pathway of the cells. The co-expression of this polypeptide significantly boosts the yield of the desired protein. In her examples, the genetically-engineered cells are often animal cells, and the co-expressed polypeptide acts as a modulator of an XBP1- or ATF6-mediated UPR pathway.
Career Highlights
Nicole works at Wyeth, a notable company in the biotechnology industry, where she leverages her expertise to advance the field further. Her research and developments have not only contributed to her professional growth but also to the wider scientific community in understanding better methods for protein synthesis.
Collaborations
Throughout her career, Nicole has collaborated with talented coworkers such as Yijie Gao and Mei Geng. These partnerships have allowed her to explore innovative ideas and enhance the outcomes of her projects, leading to groundbreaking advancements in protein production techniques.
Conclusion
Nicole M. Piche is a pivotal figure in the realm of protein production technology. Her inventions demonstrate a deep understanding of genetic engineering, with the potential to revolutionize the industry. As she continues to work at Wyeth, her ongoing contributions to biotechnology promise to inspire future innovations and developments in the field.