Nicolas Jacques

Title: Nicolas Jacques: Innovator in Pyrimidine Derivatives

Introduction

Nicolas Jacques is a notable inventor based in Liège, Belgium. He has made significant contributions to the field of pharmaceuticals, particularly in the development of pyrimidine derivatives aimed at combating gram-negative bacterial infections.

Latest Patents

Nicolas Jacques holds a patent for "Pyrimidine derivatives for prevention and treatment of gram-negative bacterial infection, contamination and fouling." This innovative patent includes new pyrimidine derivatives combined with a membrane-penetrating agent, which can also incorporate a detectable isotope. The pharmaceutical composition is designed for the treatment or prevention of gram-negative bacterial infections in host mammals. Additionally, it serves as an inhibitor of gram-negative biofilm formation on surfaces of biomaterials or medical devices, especially cardiovascular devices such as prosthetic heart valves or pacemakers. The patent also outlines the use of these derivatives as radiotracers for diagnosing or prognosing gram-negative bacterial infections.

Career Highlights

Throughout his career, Nicolas Jacques has been associated with the Université de Liège, where he has contributed to research and development in his field. His work has been instrumental in advancing the understanding and treatment of bacterial infections.

Collaborations

Nicolas has collaborated with esteemed colleagues such as Patrizio Lancellotti and Cécile Oury, enhancing the impact of his research through teamwork and shared expertise.

Conclusion

Nicolas Jacques is a pioneering inventor whose work on pyrimidine derivatives has the potential to significantly improve the treatment of gram-negative bacterial infections. His contributions to the field of pharmaceuticals are noteworthy and continue to influence medical advancements.