The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 03, 2025

Filed:

May. 21, 2021
Applicant:

Université DE Liège, Liège, BE;

Inventors:

Patrizio Lancellotti, Liège, BE;

Cécile Oury, Liège, BE;

Bernard Pirotte, Liège, BE;

Lucia Musumeci, Liège, BE;

Nicolas Jacques, Liège, BE;

Eric Goffin, Liège, BE;

Assignee:

UNIVERSITÉ DE LIÈGE, Liège, BE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/52 (2006.01); A01N 43/713 (2006.01); A01N 43/90 (2006.01); A61K 38/12 (2006.01); A61K 51/04 (2006.01); A61P 31/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/52 (2013.01); A01N 43/713 (2013.01); A01N 43/90 (2013.01); A61K 38/12 (2013.01); A61K 51/0459 (2013.01); A61P 31/04 (2018.01);
Abstract

New pyrimidine derivatives together with a membrane penetrating agent, optionally with a detectable isotope and pharmaceutical composition for use in treatment or prevention of Gram-negative bacterial infection in a host mammal in need of such treatment or prevention and use as inhibitors of Gram-negative biofilm formation on a surface of biomaterial or medical device, particularly of cardiovascular device such as prosthetic heart valve or pacemakers. New pyrimidine derivatives together with a membrane penetrating agent; for use as radiotracer in diagnosing or prognosing Gram-negative bacterial infection in a host mammal.


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