Company Filing History:
Years Active: 1997-2015
Title: Innovations and Contributions of Nicholas J Murgolo
Introduction
Nicholas J Murgolo is a prominent inventor based in Millington, NJ (US), known for his significant contributions to the field of biotechnology. With a total of 15 patents to his name, Murgolo has made remarkable advancements in medical science, particularly in the development of therapeutic polypeptides and antibodies.
Latest Patents
Among his latest patents is the invention related to C.difficile toxin B CROP domain peptides, antibodies, and complexes thereof. This invention provides polypeptide domains of toxin B (B1, B2, B3, B4) and complexes between the polypeptides and antibodies that bind specifically to the polypeptide. Additionally, methods of using these polypeptides to generate antibodies are also included. Another notable patent involves a method of reducing total cholesterol levels by administering matrilin-2 polypeptide. This invention outlines methods and compositions for treating lipid disorders by administering a polypeptide that inhibits PCSK9, along with a novel method for identifying polypeptides that interact with PCSK9.
Career Highlights
Throughout his career, Murgolo has worked with esteemed companies such as Schering Corporation and Merck Sharp & Dohme Corporation. His work in these organizations has contributed to the advancement of pharmaceutical research and development.
Collaborations
Murgolo has collaborated with notable colleagues, including Stephen Tindall and Barbara Dalie, enhancing the innovation process through teamwork and shared expertise.
Conclusion
Nicholas J Murgolo's contributions to biotechnology through his patents and collaborations highlight his role as a significant inventor in the field. His work continues to impact medical science positively.