The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 28, 1997
Filed:
Mar. 10, 1994
Applicant:
Inventors:
Barbara Dalie, Berkeley Heights, NJ (US);
Kenneth Miller, Cranford, NJ (US);
Nicholas Murgolo, Millington, NJ (US);
Stephen Tindall, Madison, NJ (US);
Assignee:
Schering Corporation, Kenilworth, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H / ; C07K / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
435 696 ; 435 701 ; 435 703 ; 435 711 ; 4352523 ; 4353201 ; 435 691 ; 435327 ; 435335 ; 435365 ; 5303873 ; 530324 ; 536 234 ; 536 235 ; 536 2353 ; 935 11 ; 935 15 ; 935 23 ; 935 71 ; 935 70 ;
Abstract
Humanized monoclonal antibodies are provided which are specific for human IL-4 and have properties unexpectedly superior to other, previously available humanized antibodies. Also provided are nucleic acids which encode the heavy and light chain variable regions of such monoclonal antibodies or antigenic fragments thereof; anti-idiotypic antibodies; and methods for detecting, measuring and immunopurifying human IL-4, and for blocking or mimicking the biological activity of human IL-4.