Company Filing History:
4 out of 37 
1 out of 2,202 
1 out of 832,891 Years Active: 1998-2001
Title: The Innovative Contributions of Nicholas J. Koszewski
Introduction
Nicholas J. Koszewski, an inventive mind located in Lexington, KY, has made significant strides in the field of pharmaceutical sciences. With a total of five patents to his name, he is recognized for his innovative solutions in the treatment of disorders related to calcium metabolism and skin conditions.
Latest Patents
Among his latest contributions are patents focusing on methods for the preparation and use of 1α,24(S)-dihydroxy vitamin D2, a compound that shows promise in pharmaceutical compositions aimed at treating various calcium metabolism disorders and skin disorders. His work involves the synthesis of synthetic 1α,24(S)-dihydroxy vitamin D, starting from ergosterol, which undergoes a detailed six-step conversion to 24-hydroxyergosterol. Following this, 24-hydroxyergosterol is subjected to irradiation and thermal conversion to 24-hydroxy vitamin D. This compound is then further transformed through an additional six steps to produce 1α,24(S)-dihydroxy vitamin D. His syntheses also led to the production of novel intermediates, adding to the potential applications of his work.
Career Highlights
Throughout his career, Koszewski has worked at Bone Care International, Inc., contributing to advancements in the understanding and treatment of bone health, among other projects. His patents reflect a commitment to combining scientific research with practical applications that address significant health challenges.
Collaborations
In his journey as an inventor, Koszewski has collaborated with notable professionals such as Charles W. Bishop and Ronald L. Horst. These partnerships highlight the collaborative nature of innovation in the pharmaceutical industry, where shared expertise often leads to groundbreaking discoveries.
Conclusion
Nicholas J. Koszewski stands as a prominent figure in the realm of pharmaceutical innovations. His patented methods and synthetic advancements underscore a deep commitment to improving health outcomes, particularly concerning calcium metabolism and skin disorders. As he continues to contribute to this vital field, his work exemplifies the power of invention and collaboration in science.