Company Filing History:
2 out of 303 
1 out of 255 
Years Active: 2018-2021
Title: Innovations of Nicholas C. Yoder
Introduction
Nicholas C. Yoder is a notable inventor based in Brookline, MA (US). He has made significant contributions to the field of biomedical research, particularly in the development of novel methods and reagents for protein ligation. With a total of three patents to his name, Yoder's work has implications for therapeutic applications and the advancement of bioconjugation techniques.
Latest Patents
Yoder's latest patents include innovative approaches to protein modification. One of his patents focuses on using sortases to install click chemistry handles for protein ligation. This invention provides methods and reagents for the installation of click chemistry handles on target proteins, as well as modified proteins that comprise these handles. Additionally, it discusses the generation and use of chimeric proteins, such as bi-specific antibodies, that are conjugated via click chemistry.
Another significant patent by Yoder involves conjugates of cysteine-engineered antibodies. This invention relates to novel cell-binding agent-cytotoxic agent conjugates, where the cell-binding agent is covalently linked to the cytotoxic agent through an engineered cysteine. The patent also outlines methods for preparing these conjugates and their applications in inhibiting abnormal cell growth or treating proliferative disorders in mammals.
Career Highlights
Throughout his career, Nicholas C. Yoder has worked with esteemed organizations, including the Whitehead Institute for Biomedical Research and Immunogen, Inc. His work in these institutions has allowed him to contribute to groundbreaking research in the field of biomedicine.
Collaborations
Yoder has collaborated with prominent scientists in his field, including Hidde L. Ploegh and Martin D. Witte. These collaborations have further enriched his research and innovations.
Conclusion
Nicholas C. Yoder's contributions to the field of biomedical research through his patents and collaborations highlight his role as an influential inventor. His work continues to pave the way for advancements in protein engineering and therapeutic applications.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.