Company Filing History:
Years Active: 2006
Title: Innovations by Newton Goncalves De Castro
Introduction
Newton Goncalves De Castro is an accomplished inventor based in Rio de Janeiro, Brazil. He has made significant contributions to the field of pharmaceuticals, particularly in developing compounds with therapeutic properties. His work focuses on creating innovative solutions for medical challenges, especially in treating heart conditions.
Latest Patents
Newton Goncalves De Castro holds a patent for a compound known as Thienylhydrazon with digitalis-like properties. This invention discloses a compound having the formula (I), wherein R is selected from the group consisting of hydrogen, alkyl of 1 to 6 carbon atoms, unsubstituted phenyl, and substituted phenyl. The compound also includes pharmaceutically acceptable salts that exhibit digitalis-like properties. The invention further details a novel method to synthesize 3,4-methylenedioxybenzoyl-2-thienylhydrazone (LASSBio-294). LASSBio-294 produces a positive inotropic effect on cardiac and skeletal muscle, making it useful for treating congestive heart failure and muscle fatigue. Notably, it lacks the toxic effects commonly associated with digitalis glycosides.
Career Highlights
Newton Goncalves De Castro is affiliated with the University System of Maryland, where he continues to engage in research and development. His work has garnered attention for its potential impact on medical treatments and patient care.
Collaborations
Throughout his career, Newton has collaborated with notable colleagues, including Roberto Takashi Sudo and Edson X Albuquerque. These partnerships have contributed to the advancement of his research and the successful development of his patented inventions.
Conclusion
Newton Goncalves De Castro exemplifies the spirit of innovation in the pharmaceutical field. His contributions, particularly through his patent on Thienylhydrazon, highlight the importance of research in developing effective treatments for serious health conditions. His work continues to inspire advancements in medical science.