Nevis L Fregien

Title: Nevis L Fregien: Innovator in Glycoprotein Research

Introduction

Nevis L Fregien is a notable inventor based in Miami, FL, recognized for his contributions to the field of glycoprotein research. He holds three patents that showcase his innovative work in biochemistry and molecular biology. His inventions have significant implications for disease diagnosis and therapy.

Latest Patents

Fregien's latest patents include the development of N-acetylglucosaminyltransferase V proteins and coding sequences. This invention provides substantially purified UDP-N-acetylglucosamine: .alpha.-6-D-mannoside .beta.-1,6-N-acetylglucosaminyl transferase (GlcNAc T-V; EC 2.4.1.155) proteins and antibodies that specifically bind GlcNAc T-V. Additionally, it includes polynucleotide sequences and oligonucleotide probes capable of hybridizing to nucleic acid sequences encoding GlcNAc T-V, along with cDNA and genomic clones. Another significant patent involves the transmembrane glycoprotein ASGP-2, which relates to a glycoprotein that is a member of the epidermal growth factor superfamily. This invention encompasses a DNA segment encoding the glycoprotein, a recombinant DNA molecule, and methods for producing the glycoprotein.

Career Highlights

Throughout his career, Nevis L Fregien has worked with esteemed organizations such as the University of Georgia Research Foundation, Inc. and Amgen Inc. His work has contributed to advancements in the understanding and application of glycoproteins in medical science.

Collaborations

Fregien has collaborated with notable colleagues, including Mohamed G Shoreibah and Beverly S Adler, who have contributed to his research endeavors.

Conclusion

Nevis L Fregien's innovative work in glycoprotein research has led to significant advancements in the field, as evidenced by his patents and collaborations. His contributions continue to impact the scientific community and pave the way for future discoveries.