Nelson N H Teng

Title: Innovations and Contributions of Nelson N H Teng

Introduction

Nelson N H Teng is a prominent inventor based in Hillsborough, California. He has made significant contributions to the field of biomedical research, particularly in the development of novel therapeutic agents. With a total of three patents to his name, Teng's work focuses on innovative methods for inducing cell membrane wounding and targeting specific cell types for treatment.

Latest Patents

Teng's latest patents include groundbreaking inventions that enhance the efficacy of cancer treatments. One of his notable patents is titled "Antibody Induced Cell Membrane Wounding." This invention provides compositions and methods for inducing cell membrane wounding, cell permeabilization, and cell killing. The composition comprises a polyvalent agent that binds to a highly expressed cell surface antigen present on the surface of a cell. This agent is preferably an IgM, and the addition of a crosslinking agent can enhance cell wounding and killing. At sublethal concentrations in vivo, these cell wounding antibodies can permeabilize cells and significantly improve responses to chemotherapeutic agents, even in patients who are refractory to such treatments.

Another significant patent is "CDIM Binding Proteins and Uses Thereof." This disclosure relates to Cell Death Inducing Molecule (CDIM) binding proteins and their pharmaceutical compositions. The invention provides CDIM binding proteins that are useful in selectively depleting and killing B cells, including neoplastic B cells. The patent also encompasses polynucleotides encoding these antigen binding proteins and methods for treating patients with B cell proliferative diseases.

Career Highlights

Throughout his career, Nelson N H Teng has worked with notable organizations, including IgM Biosciences, Inc. and Leland Stanford Junior University. His work in these institutions has allowed him to collaborate with leading experts in the field and contribute to significant advancements in biomedical research.

Collaborations

Teng has collaborated with esteemed colleagues such as Neelima M Bhat and Marcia M Bieber. These collaborations have further enriched his research and have led to innovative solutions in the treatment of various diseases.

Conclusion

Nelson N H Teng's contributions to the field of biomedical research through his patents and collaborations highlight his role as an influential inventor. His innovative approaches to cell targeting and treatment have the potential to significantly impact patient care and therapeutic strategies.