Nazila Salamat-Miller

Title: The Innovative Contributions of Nazila Salamat-Miller

Introduction

Nazila Salamat-Miller is a prominent inventor based in Arlington, MA (US). She has made significant contributions to the field of biotechnology, particularly in the development of methods for delivering lysosomal enzymes to the central nervous system (CNS). With a total of 4 patents to her name, her work has the potential to impact the treatment of lysosomal storage diseases.

Latest Patents

Among her latest patents, Nazila has developed innovative methods and compositions for CNS delivery of arylsulfatase A. One of her notable inventions provides compositions and methods for the effective treatment of lysosomal storage diseases, specifically targeting Metachromatic Leukodystrophy Disease. This invention includes a stable formulation for direct CNS intrathecal administration, which comprises an arylsulfatase A (ASA) protein, salt, and a polysorbate surfactant. Another patent focuses on stable formulations for CNS delivery of arylsulfatase A, ensuring that less than 3% of the ASA protein exists in aggregated form, thereby enhancing its therapeutic efficacy.

Career Highlights

Nazila has worked with leading companies in the biotechnology sector, including Shire Human Genetic Therapies, Inc. and Takeda Pharmaceutical Company Limited. Her experience in these organizations has allowed her to refine her expertise in genetic therapies and enzyme replacement strategies.

Collaborations

Throughout her career, Nazila has collaborated with talented professionals in her field, including Katherine Taylor and Paul Campolieto. These collaborations have contributed to her innovative research and development efforts.

Conclusion

Nazila Salamat-Miller's work exemplifies the impact of innovation in biotechnology. Her patents and contributions to the field of CNS delivery of lysosomal enzymes are paving the way for new treatments for lysosomal storage diseases.