Company Filing History:
Years Active: 2001-2008
Title: Nathalie Dubois-Stringfellow: Innovator in Polynucleotide Delivery and Cancer Treatment
Introduction
Nathalie Dubois-Stringfellow is a prominent inventor based in Berkeley, CA (US). She has made significant contributions to the fields of biotechnology and medicine, holding a total of 6 patents. Her work primarily focuses on enhancing the delivery of polynucleotides and developing human antibodies for cancer treatment.
Latest Patents
One of her latest patents is titled "Compositions and methods for polynucleotide delivery." This invention relates to compositions and methods that increase the uptake of polynucleotides into cells. Specifically, it involves vectors, targeting ligands, and polycationic agents that can enhance the frequency of polynucleotide uptake, condense polynucleotides, and inhibit serum and nuclease degradation. Another significant patent is for "Human antibodies that have MN binding and cell adhesion-neutralizing activity." This invention comprises monoclonal human MN antibodies or fragments that target specific repeats within the proteoglycan domain of the MN cell surface protein. These antibodies have applications in diagnosing and quantifying MN expression in cancer cells and tumors, and they can mediate tumor cell lysis through antibody-dependent cell-mediated cytotoxicity.
Career Highlights
Nathalie has worked with notable companies such as Chiron Corporation and Novartis Vaccines & Diagnostics, GmbH. Her experience in these organizations has contributed to her expertise in the development of innovative medical solutions.
Collaborations
Throughout her career, Nathalie has collaborated with esteemed colleagues, including John E. Murphy and Ronald N. Zuckermann. These partnerships have further enriched her research and development efforts.
Conclusion
Nathalie Dubois-Stringfellow is a trailblazer in the field of biotechnology, with a focus on polynucleotide delivery and cancer treatment. Her innovative patents and collaborations highlight her commitment to advancing medical science and improving patient outcomes.
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