Location History:
- Phoenixville, PA (US) (1991)
- King of Prussia, PA (US) (1990 - 1994)
- Wayne, PA (US) (1997)
Company Filing History:
Years Active: 1990-1997
Title: Narender K Kalyan: Innovator in Immunogen Expression and Plasminogen Activators
Introduction
Narender K Kalyan is a notable inventor based in King of Prussia, PA (US). He has made significant contributions to the field of immunology and biotechnology, holding a total of 6 patents. His work focuses on the development of innovative solutions for vaccine production and therapeutic applications.
Latest Patents
One of his latest patents involves the expression of specific immunogens using viral antigens. This patent describes chimeric DNA fragments that include a nucleotide sequence coding for the HA surface protein of an influenza A virus. The invention allows for the insertion of a foreign epitope into the nucleotide sequence of an antigenic site. Corresponding chimeric peptides, expression vectors, and transformed hosts are also provided. These peptides are instrumental in creating vaccines against specific antigens and in developing test kits for detecting exposure to these antigens. Furthermore, the peptides or their corresponding antibodies can be utilized in methods for treatment and prevention of exposure-related manifestations, including immunotherapy.
Another significant patent by Kalyan is related to des-epidermal growth factor plasminogen activators. This invention focuses on des-epidermal growth factor homologous plasminogen activators that exhibit greatly diminished affinity for liver membranes.
Career Highlights
Narender K Kalyan is currently associated with American Home Products Corporation, where he continues to innovate and contribute to advancements in biotechnology. His work has had a profound impact on the development of therapeutic solutions in the medical field.
Collaborations
Throughout his career, Kalyan has collaborated with esteemed colleagues, including Paul P Hung and Shaw-Guang L Lee. These collaborations have further enhanced the scope and impact of his research.
Conclusion
Narender K Kalyan is a distinguished inventor whose work in immunogen expression and plasminogen activators has paved the way for advancements in vaccine development and therapeutic treatments. His contributions continue to influence the field of biotechnology significantly.
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