Company Filing History:
1 out of 1,310 
1 out of 3,477 
1 out of 1,287 
Years Active: 2008-2016
Title: Naoto Kubota: Innovator in Diabetes and Arteriosclerosis Treatment
Introduction
Naoto Kubota is a prominent inventor based in Tokyo, Japan. He has made significant contributions to the fields of diabetes and arteriosclerosis treatment. With a total of 2 patents, his work focuses on developing therapeutic agents that offer effective solutions with reduced side effects.
Latest Patents
One of his latest patents is a therapeutic or prophylactic agent for diabetes. This agent includes a thiazolidine derivative as a PPAR-γ agonist, which exhibits a reduced side effect profile compared to traditional PPAR-γ agonists. The formulation includes a specific IP agonist such as beraprost sodium (BPS) and a thiazolidine derivative like pioglitazone or its pharmaceutically acceptable salts. This innovative agent demonstrates a sufficiently effective hypoglycemic action without the side effects typically associated with PPAR-γ agonists, making it a highly safe and effective option for diabetes management.
Another significant patent is a method for treating arteriosclerosis. This invention involves a scavenger receptor A expression down-regulator and a drug for preventing or treating arteriosclerosis. The active ingredient in this formulation is the C-terminal globular domain of adiponectin, adiponectin itself, or a gene encoding this domain. The invention provides a preventive or therapeutic agent capable of directly preventing intimal thickening, a key feature of arteriosclerosis. This effect is achieved by reducing the expression level of scavenger receptor A in arterial walls, thereby preventing lipid buildup in macrophages.
Career Highlights
Naoto Kubota has worked with notable organizations such as the Japan Science and Technology Agency and Toray Industries, Inc. His experience in these institutions has contributed to his expertise in developing innovative therapeutic solutions.
Collaborations
Throughout his career, Kubota has collaborated with esteemed colleagues, including Takashi Kadowaki and Tetsuya Kubota. These collaborations have further enhanced his research and development efforts in the medical field.
Conclusion
Naoto Kubota's contributions to diabetes and arteriosclerosis treatment through his innovative patents highlight his role as a significant inventor in the medical field. His work continues to pave the way for safer and more effective therapeutic options.