Nanette L S Que-Gewirth

Title: Innovations by Nanette L S Que-Gewirth

Introduction

Nanette L S Que-Gewirth is a notable inventor based in Buffalo, NY (US). He has made significant contributions to the field of biotechnology, particularly in the development of focused aptamer libraries. His work has implications for various biological applications, showcasing the intersection of innovation and practical utility.

Latest Patents

Nanette L S Que-Gewirth holds 1 patent related to focused libraries, functional profiling, laser SELEX, and DESELEX. His patent describes the construction of focused aptamer libraries in accordance with a proteome, which is a complex mixture of native biomolecules. These libraries can be screened to identify candidate aptamers with desired biological activities beyond specific binding to a target. The selected aptamers or their derivatives can be utilized for specific activities in biological systems. The processes of deconvoluting a focused library, increasing frequencies of particular aptamers (Laser SELEX), and decreasing frequencies of particular aptamers (DeSELEX) can be performed prior to assaying biological activity.

Career Highlights

Nanette L S Que-Gewirth is affiliated with Duke University, where he continues to advance research in his field. His innovative approaches have contributed to the understanding and application of aptamer technology in various biological contexts.

Collaborations

He has collaborated with notable colleagues such as Bruce A Sullenger and Juliana Layzer, further enhancing the impact of his research through teamwork and shared expertise.

Conclusion

Nanette L S Que-Gewirth's work exemplifies the vital role of innovation in biotechnology, particularly through his development of focused aptamer libraries. His contributions continue to influence the field and pave the way for future advancements.