Nan-Hsuan Wang

Title: Innovations by Inventor Nan-Hsuan Wang

Introduction

Nan-Hsuan Wang is a prominent inventor based in Taipei, Taiwan. With a total of three patents to his name, he has made significant contributions to the fields of vaccine development and glycoprotein engineering. His innovative approach and cutting-edge research have propelled advancements in biopharmaceuticals.

Latest Patents

Nan-Hsuan Wang's latest patents showcase his expertise in vaccine technology and glycoproteins. One notable patent describes "Vaccines with higher carbohydrate antigen density and novel saponin adjuvant." This invention involves vaccines that comprise carbohydrate antigen conjugated to diphtheria toxin (DT) as a carrier protein, significantly increasing the ratio of carbohydrate antigen molecules to carrier protein molecules to over 5:1. Additionally, the patent includes a novel saponin adjuvant designed to inhibit cancer cells by administering an effective dose of the mentioned vaccine.

Another significant patent focuses on "Glycosynthase variants for glycoprotein engineering and methods of use." This patent introduces novel glycosynthase enzymes that are critical for glycoprotein engineering and homogeneous antibody remodeling. The enzyme variants, EndoSd-D232M and EndoSz-D234M, exhibit glycan conjugation and modification activity at a conserved glycosylation site in the Fc region of antibodies. The research has demonstrated the effectiveness of these variants on various monoclonal antibodies (mAbs), enhancing their activity significantly.

Career Highlights

Nan-Hsuan Wang is employed at Obi Pharma Inc., where he actively contributes to innovative research and development projects. His work in the company focuses on harnessing the potential of biotechnology to create effective therapeutic solutions.

Collaborations

Throughout his career, Nan-Hsuan Wang has collaborated with esteemed colleagues, including Cheng-Der Tony Yu and Yih-Huang Hsieh. These collaborations have fostered a conducive environment for groundbreaking research and development, allowing them to share ideas and enhance their inventions.

Conclusion

Nan-Hsuan Wang continues to impact the fields of vaccine development and glycoprotein engineering with his innovative spirit and patentable inventions. His work at Obi Pharma Inc. and collaborations with fellow researchers demonstrate his dedication to advancing science and improving healthcare outcomes through inventive solutions.