The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 12, 2023
Filed:
Nov. 01, 2019
Applicant:
Obi Pharma, Inc., Taipei, TW;
Inventors:
Wei-Han Lee, Taipei, TW;
Nan-Hsuan Wang, Taipei, TW;
Chung-Hao Chang, Taipei, TW;
Yih-Huang Hsieh, Taipei, TW;
Cheng-Der Tony Yu, Anaheim, CA (US);
Cheng-Chi Wang, Taipei, TW;
Yu-Hsin Lin, Taipei, TW;
Yu-Chen Lin, Taipei, TW;
I-Ju Chen, Taipei, TW;
Assignee:
OBI PHARMA INC., Taipei, TW;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07H 15/24 (2006.01); A61K 39/39 (2006.01);
U.S. Cl.
CPC ...
A61K 39/001169 (2018.08); A61K 39/39 (2013.01); C07H 15/24 (2013.01); A61K 2039/55577 (2013.01); A61K 2039/6037 (2013.01); A61K 2039/6081 (2013.01);
Abstract
The present invention provides vaccines comprising carbohydrate antigen conjugated to a diphtheria toxin (DT) as a carrier protein, wherein the ratio of the number of carbohydrate antigen molecule to the carrier protein molecule is higher than 5:1. Also disclosed herein is a novel saponin adjuvant and methods to inhibit cancer cells, by administering an effective amount of the vaccine disclose herein.