Company Filing History:
Years Active: 2012-2014
Title: Innovations in Cancer Treatment by Nam-Soon Kim
Introduction
Nam-Soon Kim is a prominent inventor based in Daejeon, South Korea. He has made significant contributions to the field of cancer research, particularly in developing pharmaceutical compositions for cancer prevention and treatment. With a total of 2 patents, his work focuses on enhancing TRAIL sensitivity and identifying diagnostic markers for stomach cancer.
Latest Patents
Nam-Soon Kim's latest patents include a composition for enhancing TRAIL sensitivity, which comprises inhibitors for the expression or activity of TIP41 as a target gene of TRAIL sensitizer. This invention relates to a pharmaceutical composition that can prevent and treat cancer. The research demonstrates that when liver cancer cell lines resistant to TRAIL are treated with TIP41 siRNA and TRAIL, apoptosis is induced in the cancer cells. Similar effects have been observed in lung and colon cancer cases resistant to TRAIL. The induction of apoptosis was confirmed in tumor xenograft models, where treatment with TIP41 siRNA and TRAIL resulted in reduced tumor size and induced apoptosis. The MKK7/JNK signaling pathway was identified as a mediator of this apoptosis, providing strong evidence that the pharmaceutical composition can be used for cancer prevention and treatment.
Another significant patent involves the gastric carcinoma gene ZNF312b, which serves as a diagnostic marker for stomach cancer. The expression of the ZNF312b gene is specifically increased in stomach cancer, and its over-expression or under-expression affects cell proliferation and tumor formation. This marker can be effectively utilized for diagnosing stomach cancer, constructing animal models, and developing specific anticancer agents.
Career Highlights
Nam-Soon Kim is affiliated with the Korea Research Institute of Bioscience and Biotechnology, where he conducts his research. His work has garnered attention for its potential impact on cancer treatment and diagnostics.
Collaborations
Nam-Soon Kim collaborates with notable colleagues, including In-Sung Song and Cheol-Hee Kim, who contribute to his research endeavors.
Conclusion
Nam-Soon Kim's innovative work in cancer research highlights the importance of developing effective treatments and diagnostic tools. His contributions to the field are paving the way for advancements in cancer prevention and therapy.