The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 02, 2012
Filed:
Aug. 06, 2008
Nam-soon Kim, Daejeon, KR;
In-sung Song, Incheon, KR;
Nang-su OH, Gyeryong-si, KR;
So-young Jeong, Daejeon, KR;
Ga-hee Ha, Busan, KR;
Yeo-jin Jeon, Daejeon, KR;
Jeong-min Kim, Gumi-si, KR;
Cheol-hee Kim, Daejeon, KR;
Hyun-taek Kim, Daejeon, KR;
Nam-Soon Kim, Daejeon, KR;
In-Sung Song, Incheon, KR;
Nang-Su Oh, Gyeryong-si, KR;
So-Young Jeong, Daejeon, KR;
Ga-Hee Ha, Busan, KR;
Yeo-Jin Jeon, Daejeon, KR;
Jeong-Min Kim, Gumi-si, KR;
Cheol-Hee Kim, Daejeon, KR;
Hyun-Taek Kim, Daejeon, KR;
Abstract
The present invention relates to a diagnostic marker containing ZNF312b gene and the fragment thereof, a diagnostic method for stomach cancer and a screening method for stomach cancer inducers or inhibitors using the same. ZNF312b gene expression is specifically increased in stomach cancer. And the over-expression or the under-expression of the gene affects activation or inhibition of cell proliferation and tumor formation of a stomach cancer cell line and cell proliferation signal transduction system as well to induce stomach cancer at last. Therefore, ZNF312b marker gene can be effectively used for diagnosis of stomach cancer, construction of a stomach cancer animal model, prevention and treatment of stomach cancer and development of a stomach cancer specific anticancer agent.