Company Filing History:
Years Active: 1990-1991
Title: Muneo Tsujikawa: Innovator in Yeast Protein Expression
Introduction
Muneo Tsujikawa is a notable inventor based in Osaka, Japan. He has made significant contributions to the field of biotechnology, particularly in the area of yeast protein expression. With a total of 2 patents, Tsujikawa's work has advanced the methods used to produce heterologous proteins in yeast.
Latest Patents
Tsujikawa's latest patents include innovative techniques for utilizing yeast promoters. The first patent, titled "Yeast promoter truncated GAP-DH," discloses a DNA sequence of the yeast glyceraldehyde-3-phosphate dehydrogenase (GAP-DH) promoter. This patent outlines a process for preparing a heterologous protein using this DNA sequence as a promoter. The GAP-DH promoter is characterized by its small size, which allows for effective expression of physiologically active substances in yeasts and simplifies DNA recombination.
The second patent, "Yeast promoter and process for preparing heterologous protein," describes a method for producing heterologous proteins in yeast. This method involves transforming Saccharomyces cerevisiae with recombinant DNA that includes a promoter selected from yeast promoters or hybrid promoters. The patent emphasizes the use of the enhancer region of the SV40 virus and details the process of culturing transformed cells to express genes coding for heterologous proteins, such as HBsAg and Pre S-HBsAg.
Career Highlights
Muneo Tsujikawa is currently associated with The Green Cross Corporation, where he continues to innovate in the field of biotechnology. His work has been instrumental in enhancing the efficiency of protein production in yeast, which has significant implications for various applications in medicine and industry.
Collaborations
Tsujikawa has collaborated with notable colleagues, including Hajime Horii and Haruhide Kawabe. These collaborations have contributed to the advancement of research and development in yeast protein expression technologies.
Conclusion
Muneo Tsujikawa's contributions to biotechnology, particularly in yeast protein expression, have established him as a key figure in the field. His innovative patents and ongoing work at The Green Cross Corporation continue to influence the development of effective methods for producing heterologous proteins.