The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 04, 1991
Filed:
Aug. 24, 1989
Applicant:
Inventors:
Hiromichi Mukai, Osaka, JP;
Hajime Horii, Osaka, JP;
Muneo Tsujikawa, Osaka, JP;
Haruhide Kawabe, Osaka, JP;
Hirofumi Arimura, Osaka, JP;
Tadakazu Suyama, Kyoto, JP;
Assignee:
Green Cross Corporation, Osaka, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H / ; C12N / ; C12P / ;
U.S. Cl.
CPC ...
435 691 ; 435 91 ; 4351723 ; 4353201 ; 435255 ; 435256 ; 536 27 ; 935 37 ;
Abstract
A DNA sequence of the yeast glyceraldehyde-3-phosphate dehydrogenase (GAP-DH) promoter and a process for preparing a heterologous protein utilizing said DNA sequence as a promoter are disclosed, said GAP-DH promoter comprising a region upstream of an initiator codon of the GAP-DH protein up to -164 bp as a minimum unit. Since the GAP-DH promoter is small in size, a physiologically active substance can be expressed in yeasts effectively and recombination of DNA can be simplified.