Location History:
- Gaithersburg, MD (US) (2006 - 2007)
- Kyunggi-Do, KR (2001 - 2008)
Company Filing History:
Years Active: 2001-2008
Title: Innovations in Gene Therapy by Moon Jong Noh
Introduction
Moon Jong Noh is a prominent inventor based in Kyunggi-do, South Korea. He has made significant contributions to the field of gene therapy, particularly in the treatment of orthopedic diseases. With a total of 5 patents, his work has the potential to revolutionize therapeutic approaches in medicine.
Latest Patents
One of his latest patents focuses on gene therapy using TGF-β. This invention relates to a cell-mediated gene therapy treatment for orthopedic diseases, utilizing a member of the transforming growth factor-β superfamily. The research demonstrates TGF-β gene therapy as a novel treatment method for degenerative arthritis. In this study, TGF-β cDNA expression vectors were transfected into fibroblasts, which were then injected into rabbit Achilles tendons and knee joints with artificially created cartilage defects. The results showed that the partial cartilage defect treated with this gene therapy procedure was covered by newly formed hyaline cartilage, indicating successful stimulation of matrix formation.
Another significant patent involves mixed-cell gene therapy. This invention is directed towards generating a therapeutic protein at a target site by using a mixed cell composition. It includes a first population of mammalian cells that are transfected with a gene to be expressed and a second population of mammalian cells that have not been transfected. The therapeutic protein generated by the first population stimulates the second population to induce a therapeutic effect, showcasing a novel approach to enhancing gene therapy outcomes.
Career Highlights
Moon Jong Noh has worked with notable companies in the biotechnology sector, including TissueGene, Inc. and TissueGene Co. His innovative research and development efforts have positioned him as a key figure in advancing gene therapy technologies.
Collaborations
Throughout his career, he has collaborated with esteemed colleagues such as Kwan Hee Lee and Kyoung Ae Kang. These partnerships have further enriched his research and contributed to the success of his inventions.
Conclusion
Moon Jong Noh's contributions to gene therapy, particularly in orthopedic treatments, highlight his innovative spirit and dedication to advancing medical science. His patents reflect a commitment to improving patient outcomes through cutting-edge research and collaboration.