The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 28, 2006

Filed:

Mar. 05, 2003
Applicants:

Sun Uk Song, Inchon, KR;

Youngsuk Yi, Gaithersburg, MD (US);

Kwan Hee Lee, Gaithersburg, MD (US);

Moon Jong Noh, Gaithersburg, MD (US);

Inventors:

Sun Uk Song, Inchon, KR;

Youngsuk Yi, Gaithersburg, MD (US);

Kwan Hee Lee, Gaithersburg, MD (US);

Moon Jong Noh, Gaithersburg, MD (US);

Assignee:

TissueGene, Inc., Gaithersburg, MD (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61F 48/00 (2006.01); C12N 5/10 (2006.01);
U.S. Cl.
CPC ...
Abstract

The subject invention is directed to a mixed cell composition to generate a therapeutic protein at a target site by providing a first population of mammalian cells transfected or transduced with a gene that is sought to be expressed, and a second population of mammalian cells that have not been transfected or transduced with the gene, wherein endogenously existing forms of the second population of mammalian cells are decreased at the target site, and wherein generation of the therapeutic protein by the first population of mammalian cells at the target site stimulates the second population cells to induce a therapeutic effect.


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