Mohammad Ahmadian

Title: Innovations by Inventor Mohammad Ahmadian

Introduction

Mohammad Ahmadian is a notable inventor based in Bothell, WA (US). He has made significant contributions to the field of molecular biology, particularly in the development of nucleic acid molecules that have potential therapeutic applications. With a total of 2 patents, his work is paving the way for advancements in gene expression regulation.

Latest Patents

Ahmadian's latest patents include innovative methods and compositions that enhance the delivery of nucleic acids. One of his patents focuses on "Nicked or gapped nucleic acid molecules and uses thereof." This invention provides meroduplex ribonucleic acid molecules (mdRNA) that can decrease or silence target gene expression. The mdRNA comprises at least three strands forming non-overlapping double-stranded regions separated by a nick or gap, with one strand being complementary to a target gene RNA. Additionally, the patent outlines methods for decreasing expression of a target gene in cells or subjects to treat diseases related to altered gene expression.

Another significant patent by Ahmadian involves "Methods and compositions for enhancing delivery of double-stranded RNA or a double-stranded hybrid nucleic acid to regulate gene expression in mammalian cells." This invention includes a delivery-enhancing peptide that facilitates the transfection of double-stranded RNA into desired tissues of mammals, thereby improving therapeutic outcomes.

Career Highlights

Ahmadian is currently associated with Marina Biotech, Inc., where he continues to innovate in the field of biotechnology. His work is instrumental in developing new strategies for gene therapy and molecular medicine.

Collaborations

Throughout his career, Ahmadian has collaborated with esteemed colleagues, including Steven C Quay and James Mcswiggen. These collaborations have further enriched his research and contributed to the advancement of his inventions.

Conclusion

Mohammad Ahmadian's contributions to the field of molecular biology through his patents demonstrate his commitment to advancing gene therapy technologies. His innovative approaches have the potential to significantly impact the treatment of diseases related to gene expression.