Location History:
- North Potomac, MD (US) (2011 - 2013)
- Bethesda, MD (US) (2014)
- Urbana, MD (US) (2015 - 2024)
Company Filing History:
Years Active: 2011-2025
Title: Innovations in Cancer Treatment: The Contributions of Mitchell Ho
Introduction: Mitchell Ho, based in Urbana, MD, is a prominent inventor and researcher recognized for his significant contributions to the field of cancer treatment. With a remarkable portfolio of 19 patents, his work showcases innovative approaches to combatting various forms of cancer, particularly through the development of novel therapeutic molecules.
Latest Patents: Among Ho's most impactful inventions is the patent for immunotoxins with an albumin binding domain. This innovative molecule comprises a targeting moiety, an albumin binding domain, a furin cleavage sequence, and a component derived from exotoxin A. This multifunctional design aims to enhance the efficacy of cancer treatments and offers methods for producing the molecule, along with potential applications for treating or preventing cancer and inhibiting target cell growth.
Another notable patent authored by Ho involves cross-species single-domain antibodies that target mesothelin to treat solid tumors. These camel-derived monoclonal antibodies specifically bind to human and mouse mesothelin. The patent also describes chimeric antigen receptor (CAR) T cells and antibody conjugates that leverage these mesothelin-specific antibodies, opening new avenues for diagnosing and treating mesothelin-positive cancers.
Career Highlights: Throughout his career, Mitchell Ho has been affiliated with the United States of America as represented by the Secretary of the Department of Health and Human Services. His dedication to research and innovation in cancer therapies has established him as a leader in the scientific community, with a focus on ensuring that his inventions translate into meaningful clinical applications.
Collaborations: Ho's work is often in collaboration with esteemed colleagues such as Ira H Pastan and Wei Gao. Together, they have combined their expertise to advance the field of oncology, pushing the boundaries of what's possible in cancer treatment through innovative research and development.
Conclusion: Mitchell Ho stands out as an influential figure in the landscape of medical innovation, with his patents providing crucial insights into the treatment of cancers. His relentless pursuit of novel therapeutic strategies demonstrates the profound impact that dedicated inventors can have on healthcare and the lives of patients facing cancer diagnoses.