Company Filing History:
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Years Active: 2018-2019
Title: Minhee Park: Innovator in DNA Methylation and Gene Expression
Introduction
Minhee Park is a prominent inventor based in Boston, MA (US). He has made significant contributions to the field of genetic engineering, particularly in the areas of DNA methylation and gene expression modulation. With a total of 2 patents, his work is paving the way for advancements in synthetic biology.
Latest Patents
Minhee Park's latest patents include an integrated system for programmable DNA methylation. This innovative system provides engineered methods for establishing DNA adenine methylation at specific genomic locations. It utilizes DNA adenine methylation as an artificial chemical 'handle' on the genome. The systems described allow for precise placement of this handle and include molecular technologies to bind, spatially spread, and maintain it. The system comprises three functional modules: a synthetic initiator module for placing m6A at specific genomic sites, a synthetic readout module for programming m6A recognition and transcriptional logic, and a propagation module that implements a 'read-write' mechanism for chromatin spreading and epigenetic maintenance.
Another notable patent involves synthetic transcriptional and epigenetic regulators based on engineered, orthogonal zinc finger proteins. This invention provides artificial expression systems that utilize zinc-finger containing transcription factors and engineered promoters to modulate gene expression. These engineered systems facilitate the desired modulation of gene expression, showcasing the versatility and potential of synthetic biology.
Career Highlights
Minhee Park has worked with esteemed institutions such as Boston University and The General Hospital Corporation. His research and innovations have garnered attention in the scientific community, contributing to the advancement of genetic engineering techniques.
Collaborations
Minhee has collaborated with notable individuals in his field, including Ahmad S Khalil and Divya Israni. Their combined expertise has further enhanced the impact of his research and inventions.
Conclusion
Minhee Park is a leading inventor whose work in DNA methylation and gene expression is shaping the future of synthetic biology. His innovative patents and collaborations highlight his commitment to advancing genetic engineering.
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