The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 27, 2018
Filed:
Aug. 25, 2017
Trustees of Boston University, Boston, MA (US);
The General Hospital Corporation, Boston, MA (US);
Ahmad S. Khalil, Lexington, MA (US);
Divya Israni, Boston, MA (US);
Minhee Park, Boston, MA (US);
J. Keith Joung, Winchester, MA (US);
Jeffry D. Sander, Ankeny, IA (US);
TRUSTEES OF BOSTON UNIVERSITY, Boston, MA (US);
THE GENERAL HOSPITAL CORPORATION, Boston, MA (US);
Abstract
Embodiments disclosed herein provide artificial expression systems comprising the zinc-finger containing transcription factors and engineered promoters to modulate expression of genes of interest. Engineered zinc-finger transcription factors that interact with engineered promoters constitute synthetic and regulatable expression systems which facilitate the modulation of gene expression as desired.